Neurological manifestations and risk factors associated with poor prognosis in hospitalized children with Omicron variant infection

Conclusion: In this study, 32.8% of hospitalized children suffering from COVID-19 due to the Omicron variant infection experienced neurological manifestations. Baseline albumin and CK-MB levels could accurately predict poor prognosis in this patient population.What is Known:• Neurological injury has been reported in SARS-CoV-2 infection; compared with other strains, the Omicron strain is more likely to cause neurological manifestations in adults.• Neurologic injury in adults such as cerebral hemorrhage and epilepsy has been reported in patients with Omicron variant infection.What is New:• One-third hospitalized children with Omicron infection experience neurological manifestations, including central nervous system manifestations and peripheral nervous system manifestations.• Albumin and CK-MB combined can accurately predict poor prognosis (AUC 0.915), and the 30-day mortality rate of children with Omicron variant infection and neurological manifestations was 4.8%.
Source: European Journal of Pediatrics - Category: Pediatrics Source Type: research