18F-FDG and 68Ga-PSMA PET/CT in Paratesticular Mesothelioma

Clin Nucl Med. 2024 Apr 1;49(4):332. doi: 10.1097/RLU.0000000000005123.ABSTRACTA 66-year-old man with local prostate adenocarcinoma underwent radical prostatectomy (Gleason score 3 + 4 = 7, pT2c) in 2016. Four years later, he presented with a hydrocele and cystic atypical change in the left scrotum and soft tissue in the left groin. Final histopathology revealed spermatic cord mesothelioma and left hemangiosis carcinomatosa. A bone biopsy of the sacrum revealed infiltrates of a prostatic adenocarcinoma with small cell neuroendocrine differentiation. Dual-tracer PET/CT imaging using 18F-FDG and 68Ga-PSMA was able to identify local recurrence of scrotal mesothelioma and differentiate metastases of prostate cancer from malignant mesothelioma.PMID:38427957 | DOI:10.1097/RLU.0000000000005123
Source: Clinical Prostate Cancer - Category: Cancer & Oncology Authors: Source Type: research