Neonatal stress disrupts the glymphatic system development and increases the susceptibility to Parkinson's disease in later life

CONCLUSION: The results demonstrated that NMD could disrupt the development of the glymphatic system through PDGF-B signaling and increase the risk of PD later in life, indicating that alleviating neonatal stress could be beneficial in protecting the glymphatic system and reducing susceptibility to neurodegeneration.PMID:38421142 | DOI:10.1111/cns.14587

Source: CNS Neuroscience and Therapeutics - February 29, 2024 Category: Neuroscience Authors: Jian Song Zhen-Hua Li Xin-Yu Xue Jing-Cai Meng Wen-Xin Zhu Shufen Hu Guang-Yin Xu Lin-Hui Wang Source Type: research