Neutrophil-dependent hepatic platelet accumulation and liver injury revealed by acetaminophen dose-response studies

CONCLUSION: The results indicate a role of neutrophils in APAP-induced liver injury that is dependent on the APAP dose and suggest involvement of neutrophil-platelet interactions in promoting hepatic injury in experimental APAP-induced ALF.PMID:38404941 | PMC:PMC10883821 | DOI:10.1016/j.rpth.2024.102323

Source: Thrombosis and Haemostasis - February 26, 2024 Category: Hematology Authors: Anthony Schulte Dafna J Groeneveld Zimu Wei Bianca Hazel Matthew P Bernard Lauren G Poole James P Luyendyk Source Type: research