EMG Testing throughout behavioral recovery after rat sciatic nerve crush injury results in exuberant motoneuron dendritic hypertrophy

CONCLUSIONS: The ability of repeated EMG testing to so dramatically affect central plasticity following a peripheral nerve injury was unexpected. It was also unexpected that gonadal steroid hormones and/or ES, two neurotherapeutic approaches with demonstrated molecular/behavioral changes consistent with peripheral improvements in axonal repair and target reconnection, do not appear to impact central plasticity in a similar manner. The significance of peripheral EMG testing and resulting central plasticity reorganization remains to be determined.PMID:38363624 | DOI:10.3233/RNN-231379

Source: Restorative Neurology and Neuroscience - February 16, 2024 Category: Neurology Authors: Rena M Meadows Sarah M E V Richards Michelle R Kitsis Todd J Brown Kathy J Jones Dale R Sengelaub Source Type: research