PCSK9 increases vulnerability of carotid plaque by promoting mitochondrial dysfunction and apoptosis of vascular smooth muscle cells

CONCLUSION: Our findings demonstrated that PCSK9 induced morphology-related mitochondrial dysfunction and apoptosis of VSMCs, which may be related to increased vulnerability of carotid plaque.PMID:38402551 | PMC:PMC10894644 | DOI:10.1111/cns.14640

Source: CNS Neuroscience and Therapeutics - February 25, 2024 Category: Neuroscience Authors: Ran Xu Tianhua Li Jichang Luo Xiao Zhang Tao Wang Yabing Wang Yan Ma Bin Yang Jinzhu Jia Adam A Dmytriw Wenjing Li Liqun Jiao Source Type: research