Axonal excitability as an early biomarker of nerve involvement in hereditary transthyretin amyloidosis

CONCLUSIONS: These progressive changes seen across the disease spectrum in ATTRv-PN suggest that axonal excitability has utility to identify early and progressive nerve dysfunction in ATTRv, regardless of genotype.SIGNIFICANCE: Axonal excitability is a promising early biomarker of nerve dysfunction in ATTRv-PN.PMID:38377648 | DOI:10.1016/j.clinph.2024.01.006

Source: Clinical Neurophysiology - February 20, 2024 Category: Neurology Authors: Antonia S Carroll Susanna B Park Cindy S Y Lin Mark S Taylor Fiona Kwok Neil G Simon Mary M Reilly Matthew C Kiernan Steve Vucic Source Type: research