Preoperative Amiodarone and Primary Graft Dysfunction in Heart Transplantation

CONCLUSION AND RELEVANCE: A trend toward increased PGD was present in patients receiving preoperative amiodarone. This finding combined with the regression showing significantly increased odds of PGD with increasing 3 and 6 month cumulative amiodarone dose is clinically concerning. Escalation of care with pacemaker implantation was required more frequently in patients on pre-OHT amiodarone.PMID:38361242 | DOI:10.1177/10600280241232032

Source: The Annals of Pharmacotherapy - February 16, 2024 Category: Drugs & Pharmacology Authors: Abigail Servais Scott Lundgren Stephanie Bowman Douglas Stoller Adam Burdorf Marshall Hyden Brian Lowes Ronald Zolty Don Klepser Heidi Brink Source Type: research