Psoriasis and steatotic liver disease: Are PNPLA3 and TM6SF2 polymorphisms suitable for the hepato-dermal axis hypothesis?

CONCLUSIONS: MetS and T2DM confer higher odds for steatosis and advanced fibrosis in individuals with psoriasis. PNPLA3 G allele, but not TM6SF2 polymorphism, impacts a 5-fold odds of advanced liver fibrosis.PMID:38360269 | DOI:10.1016/j.aohep.2024.101477

Source: Annals of Hepatology - February 15, 2024 Category: Gastroenterology Authors: Luciana Agoglia Ana Carolina Cardoso L ívia Barbosa Cec ília Schubert Xavier Lagalhard Victer Sueli Carneiro Paulo Henrique Condeixa de Fran ça Maria Chiara Chindamo Cristiane Alves Villela-Nogueira Source Type: research