Do PET-positive supradiaphragmatic lymph nodes predict overall survival or the success of primary surgery in patients with advanced ovarian cancer?

Ovarian cancer (OC) is the leading cause of gynaecologic cancer-related deaths in the Western hemisphere [1]. Approximately 70  % of ovarian carcinomas are detected at an advanced stage [2]. Primary cytoreductive surgery (PCS), with the goal of resecting all macroscopic tumours, followed by platinum-based chemotherapy, is the standard of care for advanced OC [3,4]. Complete resection of macroscopic disease remains the mai n prognostic factor for patients with advanced OC [1]. However, even with radical cytoreductive procedures in specialised centres, complete resection of residual macroscopic disease cannot be achieved in approximately 30 % of the patients [5].
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - Category: OBGYN Authors: Tags: Full length article Source Type: research