High-content image screening to identify chemical modulators for peroxisome and ferroptosis

CONCLUSIONS: Our findings pinpoint novel cellular targets that might be involved in peroxisome homeostasis and indicate that compounds promoting peroxisomal abundance could be jointly applied with ferroptosis inducers to potentiate anticancer effect.PMID:38368371 | DOI:10.1186/s11658-024-00544-2

Source: Cellular and Molecular Biology Letters - February 17, 2024 Category: Biochemistry Authors: Daheng Zheng Fei Li Shanshan Wang Pu-Ste Liu Xin Xie Source Type: research