Pentosan polysulfate and a pigmentary maculopathy: causation versus correlation?

CONCLUSIONS: After an analysis of the literature describing a pigmentary maculopathy in IC patients on long term PPS, a causal relationship does not appear to be present. An alternate model is proposed postulating that the causative factor for the pigmentary maculopathy is the underlying inflammatory state associated with IC and not PPS use.PMID:38104330
Source: Canadian Journal of Urology - Category: Urology & Nephrology Authors: Source Type: research