A case of Stevens-Johnson syndrome treated with oral cyclosporine

J Family Med Prim Care. 2023 Dec;12(12):3425-3428. doi: 10.4103/jfmpc.jfmpc_1162_23. Epub 2023 Dec 21.ABSTRACTStevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) can occur at any age and are commonly caused by adverse drug events. Rapid diagnosis of SJS/TEN is imperative, followed by immediate cessation of offending agent and induction of appropriate treatment. Cyclosporine, a calcineurin inhibitor, has been reported to have a promising therapeutic effect in SJS/TEN patients with few side effects. Diagnosis of SJS/TEN in children is especially challenging as many of the symptoms mimic that of an upper respiratory infection, or other viral entities such as cocksackie A, roseola, or herpes simplex virus. We recommend initiating cyclosporine modified treatment, especially in children, upon any suspicion of SJS/TEN in a patient in order to halt the disease progression as early as possible.PMID:38361872 | PMC:PMC10866270 | DOI:10.4103/jfmpc.jfmpc_1162_23
Source: Herpes - Category: Infectious Diseases Authors: Source Type: research