Mechanism study of cross presentation of exogenous antigen induced by cholera toxin-like chimeric protein

In conclusion, hexameric CT-like chimeric protein with dual effects of GM1 affinity and ER retention sequence were potential in improvement of cross presentation. The results laid a foundation for designing personalized tumor vaccine based on CT-like chimeric protein molecular structure.PMID:38320931 | DOI:10.1016/j.vaccine.2024.01.075

Source: Vaccine - February 6, 2024 Category: Allergy & Immunology Authors: Xianying He Kaixiang Fan Haiyan Gong Mingqin Huang Qingsong Zeng Junjie Huang Ximing Peng Peifang Lai Yujing Lu Huaqian Wang Source Type: research