Surveillance of pneumococcal serotypes in adults hospitalised with acute lower respiratory tract infection in Bristol, UK

DISCUSSION: Among adults hospitalised with respiratory infection, pneumococcus is an important pathogen across all subgroups, including CAP+/RAD- and NP-LRTI. Despite 20-years of PPV23 use in adults ≥ 65-years and herd protection due to 17-years of PCV use in infants, vaccine-serotype pneumococcal disease still causes a significant proportion of LRTI adult hospitalizations. Direct adult vaccination with high-valency PCVs may reduce pneumococcal disease burden.PMID:38336560 | DOI:10.1016/j.vaccine.2024.02.007

Source: Vaccine - February 9, 2024 Category: Allergy & Immunology Authors: Catherine Hyams Maria Lahuerta Christian Theilacker Jade King David Adegbite Serena McGuinness Charli Grimes James Campling Jo Southern Michael W Pride Elizabeth Begier Nick Maskell Jennifer Oliver Luis Jodar Bradford D Gessner Adam Finn AvonCAP Research Source Type: research