Different levels of prepulse inhibition among patients with first-episode schizophrenia, bipolar disorder and major depressive disorder

CONCLUSION: The level of prepulse inhibition among patients with first-episode schizophrenia was the lowest, with levels among patients with BD, patients with MDD and healthy controls increasingly higher. The PSS-PPI paradigm was more effective than PSC-PPI to recognize deficits in prepulse inhibition. These results provide a basis for further research on biological indicators that can assist differential diagnoses in psychosis.PMID:38238035 | PMC:PMC10803101 | DOI:10.1503/jpn.230083
Source: Journal of Psychiatry and Neuroscience - Category: Psychiatry Authors: Source Type: research