Single  cell multi-omics of fibrotic kidney reveal epigenetic regulation of antioxidation and apoptosis within proximal tubule

CONCLUSIONS: In conclusion, as we know oxidation and apoptosis are traumatic factors during fibrosis, thus enhancing antioxidation and inhibiting the Nfix-Ifi27 pathway to inhibit apoptosis could be a potential treatment for kidney fibrosis.PMID:38270638 | PMC:PMC10811088 | DOI:10.1007/s00018-024-05118-1
Source: Cellular and Molecular Life Sciences : CMLS - Category: Cytology Authors: Source Type: research