Gut microbiota regulates hepatic ischemia-reperfusion injury-induced cognitive dysfunction via the HDAC2-ACSS2 axis in mice

CONCLUSION: These findings suggest that acetate metabolism is impaired in the hippocampus of HIRI-induced cognitive impairment mice and related to dysbiosis, leading to compromised histone acetylation.PMID:38334013 | PMC:PMC10853894 | DOI:10.1111/cns.14610

Source: CNS Neuroscience and Therapeutics - February 9, 2024 Category: Neuroscience Authors: Yanbo Liu Zhen Li Tianning Sun Zhixiao Li Anne Manyande Hongbing Xiang Zhigang He Source Type: research