Simultaneous glucose and xylose utilization by an < em > Escherichia coli < /em > catabolite repression mutant

In this study, we focus our analysis on glucose and xylose utilization as these two sugars are the primary components in lignocellulosic biomass hydrolysate, a promising renewable carbon feedstock for industrial bioprocesses. This strain is valuable to the field as it enables the use of mixed sugar sources in traditional fed-batch based approaches, whereas the wild-type carbon catabolite repression system leads to biphasic growth and possible buildup of non-preferential sugars, reducing process efficiency at scale.PMID:38289128 | DOI:10.1128/aem.02169-23

Source: Applied and Environmental Microbiology - January 30, 2024 Category: Microbiology Authors: Nicholas A Kaplan Khondokar Nowshin Islam Fiona C Kanis Jack R Verderber Xin Wang J Andrew Jones Mattheos A G Koffas Source Type: research