An empirical predictive model for determining the aqueous solubility of BCS class IV drugs in amorphous solid dispersions

CONCLUSION: The developed empirical model demonstrated robustness and predicted the aqueous solubility of model drugs from the ASDs of model polymer matrices with an accuracy greater than 80%.PMID:38318700 | DOI:10.1080/03639045.2024.2315477

Source: Drug Development and Industrial Pharmacy - February 6, 2024 Category: Drugs & Pharmacology Authors: Sridivya Raparla Charina Lampa Xiaoling Li Bhaskara R Jasti Source Type: research