Atacand to be divested to Cheplapharm in Europe
AstraZeneca has agreed to sell the commercial rights to Atacand (candesartan cilexetil) and Atacand Plus (fixed-dose combination of candesartan cilexetil and hydrochlorothiazide) in Europe to Cheplapharm Arzneimittel GmbH (Cheplapharm). Atacand is a prescription medicine for the treatment of heart failure and hypertension. (Source: World Pharma News)
Source: World Pharma News - July 24, 2018 Category: Pharmaceuticals Tags: Featured AstraZeneca Business and Industry Source Type: news

Teva Pharmaceuticals USA Issues Voluntary Nationwide Recall of Valsartan and Valsartan Hydrochlorothiazide Tablets
Teva Pharmaceuticals USA today confirmed a voluntary recall to the consumer / user level of 29 lots of single and 51 lots of combination valsartan medicines distributed under the Actavis label in the U.S. due to the detection of trace amounts of an unexpected impurity found in an active pharmaceutical ingredient (API) manufactured by Zhejiang Huahai Pharmaceutical. The impurity detected in the API is N- nitrosodimethylamine (NDMA), which is a substance that occurs naturally in certain foods, drinking water, air pollution, and industrial processes, and has been classified as a probable human carcinogen as per International ...
Source: Food and Drug Administration - July 17, 2018 Category: Food Science Source Type: news

3 Companies Recall Blood Pressure Medications Over Cancer Fears
Some drugs used to control high blood pressure and prevent heart failure were voluntarily recalled this past week due to an impurity that could possibly lead to cancer, the U.S. Food and Drug Administration said. These products — with the active ingredient valsartan, a generic drug used to treat high blood pressure — may contain N-nitrosodimethylamine (NDMA), a possible human carcinogen. The FDA asked three companies, Major Pharmaceuticals, Solco Healthcare and Teva Pharmaceuticals Industries Ltd., to recall their valsartan products. Solco and Teva were also asked to recall their drugs containing valsartan/hydr...
Source: TIME: Health - July 17, 2018 Category: Consumer Health News Authors: Jennifer Calfas Tags: Uncategorized medicine onetime Source Type: news

FDA Recalls Common Heart Drug For Potential Cancer Risk
(CNN) — The recall of a common drug used to control blood pressure and help prevent heart failure was announced by the US Food and Drug Administration on Friday, a week after 22 other countries recalled it because the drug contains a chemical that poses a potential cancer risk. Valsartan is off patent and is used as a component of other generic medicines, but not all medicines containing the ingredient are involved, according to the FDA. The US recall includes the the versions of valsartan that are made by Major Pharmaceuticals, Solco Healthcare and Teva Pharmaceuticals Industries Ltd. as well as valsartan/hydrochlor...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - July 16, 2018 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News Valsartan Source Type: news

Prinston Pharmaceutical Inc Issues Voluntary Nationwide Recall of Valsartan and Valsartan HCTZ Tablets Due to Detection of a Trace Amount of Unexpected Impurity, N-Nitrosodimethylamine (NDMA) in The Products
Prinston Pharmaceutical Inc. dba Solco Healthcare LLC. is recalling all lots of Valsartan Tablets, 40 mg, 80mg, 160mg, and 320mg; and Valsartan-Hydrochlorothiazide Tablets, 80mg/12.5mg, 160mg/12.5mg, 160mg/25mg, 320mg/12.5mg, and 320mg/25mg to the retail level. This product recall is due to the detection of a trace amount of an unexpected impurity, N-nitrosodimethylamine (NDMA), made by the manufacturer – Zhejiang Huahai Pharmaceutical Co. Ltd. -- that is used in the manufacture of the subject product lots. This impurity has been classified as a probable human carcinogen as per International Agency for Research on Ca...
Source: Food and Drug Administration - July 13, 2018 Category: Food Science Source Type: news

Class 1 Medicines Recall: Action Now including out of hours Pharmacy Level Recall: Superseded drug alert - Valsartan/Hydrochlorothiazide 160/12.5mg Film-Coated Tablets
The Medicines& Healthcare products Regulatory Agency (MHRA) issued a Class 1 Medicines Recall (Drug Alert EL (18)A/11) on 5th July 2018. Pharmacies in the UK were asked to recall all batches of v (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - July 11, 2018 Category: Drugs & Pharmacology Source Type: news

Hydrochlorothiazide and Risk of Hearing Disorder Hydrochlorothiazide and Risk of Hearing Disorder
While ototoxicity is not a known adverse effect of hydrochlorothiazide, this case series suggest there might be a causal relationship between its use and hearing disorder.Journal of Medical Case Reports (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 11, 2018 Category: Consumer Health News Tags: Internal Medicine Journal Article Source Type: news

Olmesartan Medoxomil and Hydrochlorothiazide Tablets (New - Discontinuation)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - June 21, 2018 Category: Drugs & Pharmacology Source Type: news

Possible Link Between Hydrochlorothiazide and Malignant Melanoma Possible Link Between Hydrochlorothiazide and Malignant Melanoma
Long-term hydrochlorothiazide use appears to be associated with an increased risk of malignant melanoma, researchers from Denmark report.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 30, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Hydrochlorothiazide Tied to Increased Melanoma Risk
(MedPage Today) -- Possible link pronounced for lentigo and nodular subtypes (Source: MedPage Today Dermatology)
Source: MedPage Today Dermatology - May 29, 2018 Category: Dermatology Source Type: news

Hydrochlorothiazide and Lisinopril Tablets (New - Discontinuation)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - May 22, 2018 Category: Drugs & Pharmacology Source Type: news

Hydrochlorothiazide and Skin Cancer: Raise the Red Flag Hydrochlorothiazide and Skin Cancer: Raise the Red Flag
A dramatic association has been found between this common diuretic and nonmelanoma skin cancer.Medscape Dermatology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 4, 2018 Category: Consumer Health News Tags: Dermatology Viewpoint Source Type: news

Triamterene and Hydrochlorothiazide Tablets (New - Discontinuation)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - February 23, 2018 Category: Drugs & Pharmacology Source Type: news

Hydrochlorothiazide and Skin Cancer: Should We Be Worried? Hydrochlorothiazide and Skin Cancer: Should We Be Worried?
Should we be concerned about, or take any action on, a new link found between this common antihypertensive agent and skin cancer?Medscape Internal Medicine (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 12, 2018 Category: Consumer Health News Tags: Internal Medicine Commentary Source Type: news

Hydrochlorothiazide May Up Basal, Squamous Cell Cancer Risk
Increased risk for basal cell carcinoma, squamous cell carcinoma, with dose - response relationship (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - January 6, 2018 Category: Cancer & Oncology Tags: Cardiology, Dermatology, Family Medicine, Internal Medicine, Oncology, Pharmacy, Journal, Source Type: news

Research Finds Popular Blood Pressure Drug Increases Skin Cancer Risk
This study shows a possible link between HCTZ and basal cell and squamous cell carcinomas of the skin. These are not melanomas, the deadliest form of skin cancer, but they both can pose serious health risks. This study shows an association between HCTZ and skin cancer, not proof that the medication actually causes cancer, but it’s link that needs to be studied further. In the meantime, continue to take your blood pressure medication and protect yourself from excessive sun exposure. (Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire)
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - December 6, 2017 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health Local News Syndicated Local Dr. Mallika Marshall Source Type: news

Medical News Today: Common blood pressure drug raises skin cancer risk
New research shows that people who take the popular hypertension drug hydrochlorothiazide may put themselves at a dramatically high risk of skin cancer. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - December 6, 2017 Category: Consumer Health News Tags: Melanoma / Skin Cancer Source Type: news

Ziac (Bisoprolol and Hydrochlorothiazide) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - December 5, 2017 Category: Drugs & Pharmacology Source Type: news

Hyzaar (Losartan Potassium-Hydrochlorothiazide) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - October 27, 2017 Category: Drugs & Pharmacology Source Type: news

Zestoretic (Lisinopril and Hydrochlorothiazide) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - August 3, 2017 Category: Drugs & Pharmacology Source Type: news

Vaseretic (Enalapril Maleate-Hydrochlorothiazide Tablets) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - June 8, 2017 Category: Drugs & Pharmacology Source Type: news

Uniretic (Moexipril HCl Hydrochlorothiazide Tablets) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - June 8, 2017 Category: Drugs & Pharmacology Source Type: news

Accuretic (Quinapril HCl/Hydrochlorothiazide) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - June 5, 2017 Category: Drugs & Pharmacology Source Type: news

Atacand HCT (Candesartan Cilexetil-Hydrochlorothiazide) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - April 11, 2017 Category: Drugs & Pharmacology Source Type: news

Aldactazide (Spironolactone and Hydrochlorothiazide) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - February 8, 2017 Category: Drugs & Pharmacology Source Type: news

Micardis HCT (Telmisartan and Hydrochlorothiazide Tablets) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - February 6, 2017 Category: Drugs & Pharmacology Source Type: news

Amturnide (Aliskiren, Amlodipine and Hydrochlorothiazide Tablets) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - January 30, 2017 Category: Drugs & Pharmacology Source Type: news

Tribenzor (Olmesartan Medoxomil Amlodipine Hydrochlorothiazide Tablets) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - January 30, 2017 Category: Drugs & Pharmacology Source Type: news

Maxide (Triamterene and Hydrochlorothiazide Tablets) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - January 26, 2017 Category: Drugs & Pharmacology Source Type: news

Candesartan Cilexetil Hydrochlorothiazide Tablets (candesartan cilexetil hydrochlorothiazide) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - January 12, 2017 Category: Drugs & Pharmacology Source Type: news

Teveten HCT (Eprosartan Mesylate Hydrochlorothiazide Tablets) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - January 5, 2017 Category: Drugs & Pharmacology Source Type: news

Avalide (Irbesartan-Hydrochlorothiazide) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - December 12, 2016 Category: Drugs & Pharmacology Source Type: news

Tekturna HCT (Aliskren and Hydrochlorothiazide Tablets) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - November 28, 2016 Category: Drugs & Pharmacology Source Type: news

Irbesartan and Hydrochlorothiazide Tablets USP (New - Discontinuation)
Updated Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - November 18, 2016 Category: Drugs & Pharmacology Source Type: news

Inderide (Propranolol Hydrochloride and Hydrochlorothiazide) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - November 18, 2016 Category: Drugs & Pharmacology Source Type: news

Teva receives approval for generic Tribenzor in US
Teva Pharmaceutical Industries has secured approval for generic Tribenzor (olmesartan medoxomil, amlodipine and hydrochlorothiazide) tablets in the US and is in the last stages of launch preparation. (Source: Pharmaceutical Technology)
Source: Pharmaceutical Technology - November 9, 2016 Category: Pharmaceuticals Source Type: news

Exforge HCT (Amlodipine Valsartan Hydrochlorothiazide Tablets) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - October 31, 2016 Category: Drugs & Pharmacology Source Type: news

Study suggests link between commonly used antihypertensive drug and skin cancer
Despite its widespread use as a guideline-recommended, first-line agent for the treatment of hypertension, hydrochlorothiazide (HCTZ) may contribute to an increased risk of skin cancer, according to Armand B. Cognetta Jr., MD, and his associates in the division of dermatology, Mohs Micrographic... (Source: Skin and Allergy News)
Source: Skin and Allergy News - September 17, 2016 Category: Dermatology Source Type: news

CardioBrief: Can 50 Million Prescriptions Be Wrong?
(MedPage Today) -- Innovative trial to determine actual benefit of hydrochlorothiazide (Source: MedPage Today Public Health)
Source: MedPage Today Public Health - August 16, 2016 Category: American Health Source Type: news

Benicar HCT (Olmesartan Medoxomil-Hydrochlorothiazide) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - July 26, 2016 Category: Drugs & Pharmacology Source Type: news

hydrochlorothiazide, (Hydrodiuril, Ezide, Hydro-Par [discontinued]), Microzide, and many others
Title: hydrochlorothiazide, (Hydrodiuril, Ezide, Hydro-Par [discontinued]), Microzide, and many othersCategory: MedicationsCreated: 12/31/1997 12:00:00 AMLast Editorial Review: 6/30/2016 12:00:00 AM (Source: MedicineNet High Blood Pressure General)
Source: MedicineNet High Blood Pressure General - June 30, 2016 Category: Cardiology Source Type: news

hydrochlorothiazide (Microzide, Hydrodiuril, Ezide, and Hydro-Par have been discontinued)
Title: hydrochlorothiazide (Microzide, Hydrodiuril, Ezide, and Hydro-Par have been discontinued) Category: Medications Created: 12/31/1997 12:00:00 AM Last Editorial Review: 6/30/2016 12:00:00 AM (Source: MedicineNet High Blood Pressure General)
Source: MedicineNet High Blood Pressure General - June 30, 2016 Category: Cardiology Source Type: news

Valsartan and Hydrochlorothiazide Tablet, Film Coated (New - Discontinuation)
Updated Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - February 17, 2016 Category: Drugs & Pharmacology Source Type: news

lisinopril and hydrochlorothiazide, Zestoretic, Prinzide
Title: lisinopril and hydrochlorothiazide, Zestoretic, PrinzideCategory: MedicationsCreated: 7/23/1998 12:00:00 AMLast Editorial Review: 1/14/2016 12:00:00 AM (Source: MedicineNet High Blood Pressure General)
Source: MedicineNet High Blood Pressure General - January 14, 2016 Category: Cardiology Source Type: news

Hydrochlorothiazide Tablets by Unichem Pharmaceuticals (USA), Inc: Recall - Potential Presence of Foreign Tablets Contamination
Missing a dose of Hydrochlorothiazide could result in uncontrolled blood pressure or swelling caused by excess fluid (edema). (Source: FDA MedWatch)
Source: FDA MedWatch - August 1, 2015 Category: American Health Source Type: news

Unichem Pharmaceuticals (USA), Inc. Issues a Voluntary Nationwide Recall of Hydrochlorothiazide Tablets Due to the Potential Presence of Foreign Tablets
Unichem Pharmaceuticals (USA), Inc. (Unichem) is voluntarily recalling one lot of Hydrochlorothiazide Tablets 25 mg 1000-count bottle to the consumer level. This recall has been initiated as a precautionary measure due to the identification of a Clopidogrel tablet found in a bottle of the product. (Source: Food and Drug Administration)
Source: Food and Drug Administration - August 1, 2015 Category: Food Science Source Type: news

captopril and hydrochlorothiazide, Capozide
Title: captopril and hydrochlorothiazide, CapozideCategory: MedicationsCreated: 6/6/1999 12:00:00 AMLast Editorial Review: 6/17/2015 12:00:00 AM (Source: MedicineNet Medications General)
Source: MedicineNet Medications General - June 17, 2015 Category: Drugs & Pharmacology Source Type: news

bisoprolol and hydrochlorothiazide, Ziac
Title: bisoprolol and hydrochlorothiazide, ZiacCategory: MedicationsCreated: 12/31/1997 12:00:00 AMLast Editorial Review: 5/15/2015 12:00:00 AM (Source: MedicineNet Medications General)
Source: MedicineNet Medications General - May 15, 2015 Category: Drugs & Pharmacology Source Type: news

valsartan/hydrochlorothiazide (Diovan HCT)
Title: valsartan/hydrochlorothiazide (Diovan HCT)Category: MedicationsCreated: 3/2/2005 12:00:00 AMLast Editorial Review: 12/23/2014 12:00:00 AM (Source: MedicineNet Heart General)
Source: MedicineNet Heart General - December 23, 2014 Category: Cardiology Source Type: news

Hydrochlorothiazide Tied to Non - Melanoma Skin Cancer Risk
Dose - response association seen for basal cell and especially squamous cell carcinoma (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - November 11, 2014 Category: Cancer & Oncology Tags: Cardiology, Dermatology, Family Medicine, Internal Medicine, Oncology, Pathology, Pharmacy, Journal, Source Type: news