GATA6 Suppresses Lung Adenocarcinoma Progression by Activating CFTR to Modulate Arachidonic Acid Metabolism

CONCLUSION: The activation of CFTR by GATA6 hampered LUAD progression by modulating the AA metabolism pathway, suggesting that GATA6/CFTR axis might be a therapeutic target for LUAD patients.PMID:38299406 | DOI:10.2174/0113862073269158240122072743

Source: Combinatorial Chemistry and High Throughput Screening - February 1, 2024 Category: Chemistry Authors: Yong Lin Yushan Chen Yi Zhang Jianming Weng Rongqiang Shen Wenshan Zhang Yulin Lin Source Type: research