Corneal acetylcholine regulates sensory nerve activity via nicotinic receptors

CONCLUSIONS: The corneal epithelium can synthesize and release acetylcholine. Corneal acetylcholine can excite sensory nerves via nicotinic receptors containing the α4 subunit. Therefore, corneal acetylcholine may be one of the important regulators of corneal nerve activity arranging ocular surface condition and sensation.PMID:38242319 | DOI:10.1016/j.jtos.2024.01.006

Source: The Ocular Surface - January 19, 2024 Category: Opthalmology Authors: Takayoshi Masuoka Takeshi Kiyoi Shijie Zheng Qiang He Li Liu Junsuke Uwada Ikunobu Muramatsu Source Type: research