Morphological, molecular, and functional characterization of mouse glutamatergic myenteric neurons

In conclusion, VGLUT2-ENs are a functionally unique group of enteric neurons with single aborally projecting long axons that traverse multiple myenteric ganglia and are activated indirectly by colorectal mechanical stretch. This knowledge will provide a solid foundation for subsequent studies on the potential interactions of VGLUT2-EN with extrinsic colorectal afferents via glutamatergic neurotransmission.PMID:38193160 | DOI:10.1152/ajpgi.00200.2023
Source: Am J Physiol Gastroi... - Category: Gastroenterology Authors: Source Type: research