Relationships of Proton Pump Inhibitor-Induced Renal Injury with CYP2C19 Polymorphism: A Retrospective Cohort Study

In conclusion, this retrospective study showed that CYP2C19 metabolizer status was associated with the time to a 30% eGFR decrease in patients treated with lansoprazole, but not with esomeprazole, rabeprazole, or vonoprazan.PMID:38258325 | DOI:10.1002/cpt.3183

Source: Clinical Pharmacology and Therapeutics - January 23, 2024 Category: Drugs & Pharmacology Authors: Rika Fukui Satoshi Noda Yoshito Ikeda Yuichi Sawayama Tomohiro Terada Yoshihisa Nakagawa Shin-Ya Morita Source Type: research