Identification and characterization of a novel nematode pan allergen (NPA) from < i > Wuchereria bancrofti < /i > and their potential role in human filarial tropical pulmonary eosinophilia (TPE)

Conclusions/SignificanceBased on our results, we conclude that the NPA protein secreted by the microfilariae of W. bancrofti may play a significant role in the pathology of TPE syndrome in LF infected individuals. Further studies on this molecule can help design an approach to neutralize the NPA in an attempt to reduce the pathology associated with TPE in LF infected subjects.
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research