Serum Galectin ‐1, Galectin‐9, and YKL‐40 levels in bipolar disorder and their relationship with cognitive functions

Discussion and conclusionStatistically significant low levels of serum Galectin-1, Galectin-9, and YKL-40 detected in the patient group suggest that these parameters have important roles in neuroinflammation. The statistically higher Stroop and trail-making test scores of the patient group compared to the control group indicates that the cognitive performance of the patient group was weaker. Also, the positive correlation between Galectin-1, Galectin-9, and YKL-40 levels and cognitive performance suggests that these molecules may have a neuroprotective role. We think that the present study will contribute to this field where there is very limited data in the literature.

Source: Brain and Behavior - February 13, 2024 Category: Neurology Authors: Elcicek Selahaddin, Demir Bahadir, Sahin Sengul, Taysi Seyithan, Ulusal Hasan, Elboga G ülcin, Altindag Abdurrahman Tags: ORIGINAL ARTICLE Source Type: research