Elevated Ferritin Prior to Collection and Mobilization May Predict Low Stem Cell Yield

Bone marrow transplantation requires collecting an adequate number of hematopoietic stem cells to ensure successful engraftment. Ferritin, a key iron storage protein and acute phase reactant, is routinely evaluated during pre-collection visits to assess for iron deficiency or overload and may impact stem cell capture. Physicians must anticipate difficulties in stem cell capture, and pre-collection ferritin levels may be helpful.

Source: Biology of Blood and Marrow Transplantation - February 1, 2024 Category: Hematology Authors: Charles Joseph Weeks, Danielle Bradshaw, Mohammad A H Mian, Anvay Shah, Katherine J Kim, Sujith Abbagoni, Anand P Jillella, Vamsi Kota Tags: 201 Source Type: research