Long-Term Outcomes of Autologous Stem Cell Transplant with Thiotepa, Busulfan, and Cyclophosphamide Conditioning for Patients with Central Nervous System Lymphoma
Central nervous system lymphoma (CNSL) is associated with dismal outcomes and short survival. Treatment of CNSL involves high-dose chemotherapy followed by consolidative autologous stem cell transplant (ASCT). Thiotepa, busulfan and cyclophosphamide (TBC) conditioning improves progression-free survival in CNSL, but further data is needed to evaluate long-term toxicity and survival outcomes. We hereby report our experience in patients with primary and secondary CNSL who received TBC conditioning for ASCT.
Source: Biology of Blood and Marrow Transplantation - Category: Hematology Authors: Aseel Alsouqi, Zhexi Lu, Ziyu Huang, Frank Lieberman, Megan Mantica, Jan Drappatz, Rafic Farah Tags: 207 Source Type: research
More News: Biology | Chemotherapy | Hematology | Lymphoma | Primary CNS Lymphoma | Stem Cell Therapy | Stem Cells | Toxicology | Transplants