Choroid plexus enlargement in mild cognitive impairment on MRI: a large cohort study

ConclusionWe identified a relationship between CPV and MCI, which could not be explained by the degree of brain atrophy. Our results support CP dysfunction in MCI.Clinical relevance statementChoroid plexus volume measurement may serve as a valuable imaging biomarker for diagnosing and monitoring mild cognitive impairment. The enlargement of the choroid plexus, independent of brain atrophy, suggests its potential role in mild cognitive impairment pathology.Key Points• The study examines choroid plexus volume in relation to cognitive decline in elderly.• Enlarged choroid plexus volume independently indicates mild cognitive impairment presence.• Choroid plexus volume could be a specific biomarker for early mild cognitive impairment diagnosis.
Source: European Radiology - Category: Radiology Source Type: research