Impact of metformin and Dysosmobacter welbionis on diet-induced obesity and diabetes: from clinical observation to preclinical intervention

Conclusions/interpretationD. welbionis abundance is influenced by metformin treatment and associated with prebiotic response, liver health and glucose metabolism in humans with obesity and diabetes. This study suggests thatD. welbionis may play a role in metabolic health and warrants further investigation.Clinical trialNCT03852069Graphical Abstract
Source: Diabetologia - Category: Endocrinology Source Type: research