Proteomic Associations Of N-terminal-pro Hormone Bnp In Heart Failure With Preserved Ejection Fraction In Two Cohorts

N-terminal-pro natriuretic peptide (NT-proBNP) levels are variably elevated in heart failure with preserved ejection fraction (HFpEF), even among patients with increased left ventricular filling pressures. NT-proBNP levels are prognostic in HFpEF, and NT-proBNP levels have been used as an inclusion criterion for several recent landmark randomized clinical trials but the underlying biologic differences between HFpEF patients with high and low NT-proBNP levels are not fully understood.

Source: Journal of Cardiac Failure - January 1, 2024 Category: Cardiology Authors: Joe David Azzo, Marie-Joe Dib, Lei Zhao, Zhaoqing Wang, Christina Ebert, Oday Salman, Sushrima Gan, Payman Zamani, Jordana (Jordy) Cohen, Vanessa van Empel, Mark Richards, Robert Doughty, Ali Javaheri, Peter Schafer, Dietmar Seiffert, Francisco Ramirez-Va Tags: JNC-001 Source Type: research