Icariin Inhibits Overexpression and Aggregation of α-Synuclein in A53T α-Synuclein Transgenic Mice by Regulating Parkin and PLK2

CONCLUSIONS: ICA alleviated motor impairments in A53T mice, an effect which may be associated with the decreased phosphorylation and aggregation of α-synuclein through PLK2 and parkin regulation.PMID:38176950 | DOI:10.31083/j.jin2206166

Source: Journal of Integrative Neuroscience - January 4, 2024 Category: Neuroscience Authors: Denglei Ma Cong Shen Xu Zhang Lan Zhang Lin Li Source Type: research