Lentiviral Transduction-based CRISPR/Cas9 Editing of < em > Schistosoma mansoni < /em > Acetylcholinesterase

CONCLUSION: Taken together, electroporation is more efficient than lentiviral transduction in the delivery of CRISPR/Cas9 into schistosomes for programmed genome editing. The exploration of tactics for enhancing CRISPR/Cas9 gene editing provides the basis for the future improvement of programmed genome editing in S. mansoni.PMID:38178986 | PMC:PMC10761339 | DOI:10.2174/1389202924666230823094608

Source: Current Genomics - January 5, 2024 Category: Genetics & Stem Cells Authors: Xiaofeng Du Donald P McManus Juliet D French Haran Sivakumaran Rebecca L Johnston Olga Kondrashova Conor E Fogarty Malcolm K Jones Hong You Source Type: research