Effects of isoflurane anaesthesia depth and duration on renal function measured with [99mTc]Tc-mercaptoacetyltriglycine SPECT in mice

ConclusionsDeep anaesthesia and prolonged low anaesthesia should be avoided during renal scintigraphy because they result in prolonged blood clearance half-life, delayed renal influx and/or later Tmax. Vice versa, low anaesthesia with high respiratory rates of 80 –90 rpm and short duration (≤ 20 min) should be preferred to obtain representative data with low variance.

http://link.springer.com/10.1186/s13550-023-01065-3

Source: EJNMMI Research - January 5, 2024 Category: Radiology Source Type: research