Gastric Carcinoma with low ROR alpha, low E- Cadherin and High LAPTM4B Immunohistochemical Profile; is associated with unfavorable prognosis in Egyptian patients

In conclusion, RORα and LAPTM4B may have crucial role in GC aggressiveness. The predominance of low RORα, high LAPTM4B, and heterogeneous or negative E-Cadherin immunohistochemical profile in GC cases with unfavorable pathological parameters suggested that this profile may predict tumor behavior.PMID:38031398 | DOI:10.1080/15321819.2023.2279639

Source: Journal of Immunoassay and Immunochemistry - November 30, 2023 Category: Biochemistry Authors: Shereen Nagib El Mashad Mona Abd El Halim Kandil Taysseer Abd El-Hamid Talab Abd El Naby Saied Abd El Naby Mervat Mahmoud Sultan Ahmed Sohaib Aiat Shaban Hemida Source Type: research