Comparison of neuroprotective effects of a topiramate-loaded biocomposite based on mesoporous silica nanoparticles with pure topiramate against methylphenidate-induced neurodegeneration

CONCLUSION: TPM-loaded nanoparticles could be used as neuroprotective agents against MPH-induced neurodegeneration by improving seizure parameters and reducing inflammatory, oxidant, and apoptotic factors.PMID:38170306 | DOI:10.1007/s11033-023-09011-1

Source: Molecular Biology Reports - January 3, 2024 Category: Molecular Biology Authors: Erfan Pari Mohammad Sheibani Mohammad Reza Sazegar Saeedeh Mir Ashrafsadat Moazam Mina Khalilzadeh Manijeh Motevalian Source Type: research