Indirubin mediates adverse intestinal reactions in guinea pigs by downregulating the expression of AchE through AhR

This study showed that the inhibition of AchE expression by indirubin plays a key role in the occurrence of adverse reactions to indirubin and that the underlying mechanism is related to AhR-mediated AchE downregulation.PMID:38164702 | DOI:10.1080/00498254.2023.2297745

Source: Xenobiotica - January 2, 2024 Category: Research Authors: Xiaoting Xu Reham Taha Chenghan Chu Li Xiao Tao Wang Xinzhi Wang Xin Huang Zhenzhou Jiang Lixin Sun Source Type: research