Doping control approach: Identification of equine in vitro metabolites of voxelotor (GBT440), a hemoglobin S polymerization inhibitor

CONCLUSIONS: The data acquired will accelerate the identification of voxelotor and related compounds, aiding in the detection of their illicit use in competitive sports. It is crucial to emphasize that the metabolites detailed in this manuscript were identified through in vitro experiments and their detection in an in vivo study may not be guaranteed.PMID:38124165 | DOI:10.1002/rcm.9671

Source: Rapid Communications in Mass Spectrometry : RCM - December 21, 2023 Category: Chemistry Authors: Michael Benedict Subhahar Abdul Khader Karakka Kal Moses Philip Meleparappil Muhammed Ajeebsanu Tajudheen K Karatt Zubair Perwad Source Type: research