Calcium Activation of the Androgen Receptor in Prostate Cells

CONCLUSIONS: The results of this study show that calcium activates AR and increases cell growth and that calcium channels are overexpressed in hormone-responsive and hormone-resistant prostate cancer cells. Taken together, the results suggest a novel role of calcium in the castration-resistant phenotype.PMID:38131032 | PMC:PMC10733593 | DOI:10.1155/2023/9907948

Source: International Journal of Endocrinology - December 22, 2023 Category: Endocrinology Authors: Zeina W Sharawi Sawsan M Khatrawi Qiaochu Wang Hongzhao Zhou Kedra Cyrus Gai Yan Becky Hoxter Bassem R Haddad Mary Beth Martin Source Type: research