Immunogenicity and Therapeutic Efficacy of a Sendai-Virus-Vectored HSV-2 Vaccine in Mouse and Guinea Pig Models

CONCLUSIONS: The replication-defective recombinant Sendai viruses conveying HSV-2-gD and ICP27 proteins showed great immunogenicity and potential for preventing recurrent HSV-2 disease.PMID:38140157 | DOI:10.3390/vaccines11121752

Source: Herpes - December 23, 2023 Category: Infectious Diseases Authors: Xiuxiu Ren Wenhao Su Shishi Li Tingting Zhao Qiufang Huang Yinan Wang Xiaojie Wang Xiaohuan Zhang Jiangbo Wei Source Type: research