Up-regulation of scleral C5b-9 and its regulation of the NLRP3 inflammasome in a form-deprivation myopia mouse model

CONCLUSIONS: Complement cascades are activated in FD myopia model. Upregulation of C5b-9 might participate in scleral remodeling during myopia progression via regulation of NLRP3 inflammasome activation.PMID:38118343 | DOI:10.1016/j.imbio.2023.152776

Source: Immunobiology - December 20, 2023 Category: Allergy & Immunology Authors: Kang Xiao Zhengyu Chen Songqing He Qin Long Source Type: research