Treatment guesses in the Treatment for Adolescents with Depression Study: Accuracy, unblinding and influence on outcomes

CONCLUSIONS: For Treatment for Adolescents with Depression Study, treatment guesses strongly predicted outcomes and may have led to the exaggeration of drug effectiveness in the absence of actual effects. The integrity of double-blinding in trials should be routinely assessed and reported.PMID:38126083 | DOI:10.1177/00048674231218623

Source: The Australian and New Zealand Journal of Psychiatry - December 21, 2023 Category: Psychiatry Authors: Jon Jureidini Joanna Moncrieff Julie Klau Natalie Aboustate Melissa Raven Source Type: research