Dem-Aging: autophagy-related pathologies and the “two faces of dementia”

In this study, we fused multiomic assessments in established NCL models with similar data on the more common late-onset neurodegenerative conditions in order to test the hypothesis of shared molecular fingerprints critical to the underlying pathological mechanisms. Our aim, ultimately, is to combine data analysis, cell models, and omic strategies in an effort to trace new routes to therapies that might readily be applied in the most common forms of dementia.
Source: Neurogenetics - Category: Genetics & Stem Cells Source Type: research