Neuropsychological functioning during chemotherapy with temozolomide in high-grade glioma patients: a retrospective single centre study

ConclusionsTMZ proved to be a secure treatment with no negative side effects on cognition and on level of daily autonomy, even at the highest dosage used. This is a positive finding which enables clinicians to reassure patients about the absence of significant negative effects of TMZ on their daily life functioning. In this view, eventual cognitive changes during treatment might not be attributed to chemotherapy but to other events such as tumour relapse.
Source: Journal of Neuro-Oncology - Category: Cancer & Oncology Source Type: research