Antileishmanial effects of γCdcPLI, a phospholipase A2 inhibitor from Crotalus durissus collilineatus snake serum, on Leishmania (Leishmania) amazonensis

CONCLUSIONS: γCdcPLI is an interesting tool for the discovery of new essential targets on the parasite, as well as an alternative compound to improve the effectiveness of the leishmaniasis treatment.PMID:38018570 | PMC:PMC10690931 | DOI:10.1590/0074-02760220225

Source: Memorias do Instituto Oswaldo Cruz - November 29, 2023 Category: Infectious Diseases Authors: Marina Neves Gon çalves Daiana Silva Lopes Samuel Cota Teixeira Thaise Lara Teixeira Vitor de Freitas T ássia Rafaella Costa Sarah Natalie Cirilo Gimenes Isabella Mitie de Camargo Guilherme de Souza Marcelo Santos da Silva Fernanda Van Petten de Vasconc Source Type: research