The regulatory role and mechanism of USP14 in endothelial cell pyroptosis induced by coronary heart disease

CONCLUSION: USP14 stabilizes NLRP3 protein expression through deubiquitination, thereby facilitating endothelial cell pyroptosis in CHD. miR-15b-5p restrains endothelial cell pyroptosis by targeting USP14 expression.PMID:38073382 | DOI:10.3233/CH-232003

Source: Clinical Hemorheology and Microcirculation - December 11, 2023 Category: Hematology Authors: Jie Gao Zhao Gao Source Type: research