Yacon root extract improves lipid metabolism in hyperlipidemic rats by inhibiting HMGCR expression and activating the PPAR < em > α < /em > /CYP7A1/CPT-1 pathway

CONCLUSION: Yacon root extract can reduce serum TG and TC levels in HLP rats possibly by inhibiting HMGCR expression and activating the PPARα/CYP7A1/CPT-1 signaling pathway, thereby promoting fatty acid β oxidation and bile acid metabolism.PMID:38081618 | PMC:PMC10713474 | DOI:10.12122/j.issn.1673-4254.2023.11.20

Source: Journal of Southern Medical University - December 11, 2023 Category: Universities & Medical Training Authors: S Gong J Yang J Zhang X Wu S Jiang Y Zhang G Gong N Wu J Sun Z Wu Source Type: research