Optic nerve thickening on high-spatial-resolution MRI predicts early-stage postlaminar optic nerve invasion in retinoblastoma

ConclusionPostlaminar optic nerve thickening can predict early-stage postlaminar optic nerve invasion in retinoblastoma.Clinical relevance statementThis study provides an additional tool for clinicians to help determine postlaminar optic nerve invasion, which is a risk factor for developing metastatic disease in retinoblastoma patients.Key Points• The diagnostic accuracy of contrast-enhanced MRI for detecting postlaminar optic nerve invasion is limited in retinoblastoma patients.• Optic nerve thickening can predict postlaminar optic nerve invasion.• A prediction model combining MRI features has a high sensitivity and specificity for detecting postlaminar optic nerve invasion.
Source: European Radiology - Category: Radiology Source Type: research