A single-center, retrospective analysis to compare measurement of fibrinogen using the TEG6 analyzer to the Clauss measurement in children undergoing heart surgery

CONCLUSION: This study demonstrates that whole blood functional fibrinogen, as estimated by TEG6s, tends to overestimate baseline plasma fibrinogen levels in pediatric age groups but aligns more accurately post-cardiopulmonary bypass, particularly in neonates and infants, suggesting its potential as a point-of-care tool in pediatric cardiac surgery. However, the variability in TEG6s performance before and after bypass highlights the need for careful interpretation of its results in clinical decision-making. Despite its contributions to understanding TEG6s in pediatric cardiac surgery, the study's design and inherent biases warrant cautious application of these findings in clinical settings.PMID:38071737 | DOI:10.1111/pan.14820

Source: Paediatric Anaesthesia - December 10, 2023 Category: Anesthesiology Authors: Nischal Gautam Vy Tran Evelyn Griffin Jehan Elliott Eric Rydalch Kelbie Kerr Alex J Wilkinson Xu Zhang Sepideh Saroukhani Source Type: research